GATE Syllabus for Biochemistry (XL-I)

Applicants are advised to go through this post in order to check the GATE Biochemistry syllabus. Candidates who are going to appear in the upcoming GATE exam for Biochemistry branch can get all latest updates on GATE syllabus for Biochemistry as it has been recently declared by the conducting authority.

Part 1:

Importance of water; Organization of life; Structure and function of biomolecules: Amino acids, Lipids, Carbohydrates, Nucleic acids and Proteins; Protein structure, folding and function: Hemoglobin, Myoglobin, Lysozyme, Carboxypeptidase, Ribonuclease A, and Chymotrypsin.

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Part 2:

Enzyme kinetics including its regulation and inhibition, Vitamins and Coenzymes; Metabolism and bioenergetics; Generation and utilization of ATP; Metabolic, pathways and their regulation: glycolysis, TCA cycle, pentose phosphate pathway,oxidative phosphorylation, gluconeogenesis, glycogen and fatty acid metabolism; Metabolism of Nitrogen containing compounds: nitrogen fixation, amino acids and nucleotides. Photosynthesis: Calvin cycle.

Part 3:

Biochemical separation techniques: ion exchange, size exclusion and affinity chromatography, UV-visible Characterization of bio molecules by electrophoresis and fluorescence spectroscopy and Mass spectrometry.

Part 4:

Biological membranes; Cell structure and organelles; Transport across membranes; Hormones and neurotransmitters; Signal transduction

Part 5:

DNA replication, Biochemical regulation of gene expression; transcription and translation; Recombinant DNA technology and applications: site directed mutagenesis, PCR, and DNA-microarray.

Part 6:

Complement system; Immune system: Active and passive immunity; Antibody structure, Cells of the immune system: T, B and macrophages; T and B cell activation; function and diversity; Major histo compatibility complex; Immunological techniques: Immuno diffusion, immune electrophoresis, T cell receptor; RIA and ELISA.

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